Cardiogenic shock is a serious life-threatening condition affecting almost 10% of patients suffering from acute coronary syndrome. When untreated, it can rapidly progress causing collapse of circulation and sudden death. Despite contemporary improvements in diagnostic and treatment options, mortality remains incredibly high, reaching nearly 50%.
Currently available mechanical circulatory support devices can replace the function of the heart and/or lungs, thereby essentially eliminating the primary cause. However, cardiogenic shock is not only an isolated decrease in cardiac function but a rapidly progressing multiorgan dysfunction accompanied by severe cellular and metabolic abnormalities. The window for successful treatment is relatively narrow and when missed, even the elimination of underlying primary cause is not enough to reverse this vicious circle.
Full text/protocol - on request
What we accomplished so far
Our preliminary results showed better prediction compared to standard models (e.g., the ORBI score) and were accepted for the oral presentation at the ESC Acute CardioVascular Care 2022.
#STOP SHOCK is designed to allow new potential CS predictors to be added and tested in the future ensuring that the model keeps pace with contemporary research.
Sign-up your institution for prospective validation
Get access to dedicated STOP SHOCK smartphone applications and work with us on prospective validation and continuous model improvement.
Sign-up your institution for STOP SHOCK CS registry
Help with retrospective or prospective patient registration. Established ACS STOP SHOCK patient database will be available to all contributing members with STOP SHOCK not being the end but a beginning of international research cooperation on cardiogenic shock.
Score To Predict SHOCK