Cardiogenic shock
Cardiogenic shock is a serious life-threatening condition affecting almost 10% of patients suffering from acute coronary syndrome.
Despite recent improvements in diagnostic and treatment options, mortality remains incredibly high, reaching nearly 50%.
The ability to identify high-risk patients prior to the development of CS could allow pre-emptive measures, such as the implantation of pMCS, and thus prevent CS, leading to improved survival.
#STOPSHOCK
#STOPSHOCK is a novel, continuously updated, A.I. based scoring system for the prediction of cardiogenic shock in patients with acute coronary syndrome. STOPSHOCK 2.0 model is currently undergoing external validation.
About
Cardiogenic shock is a serious life-threatening condition affecting almost 10% of patients suffering from acute coronary syndrome. When untreated, it can rapidly progress causing collapse of circulation and sudden death. Despite contemporary improvements in diagnostic and treatment options, mortality remains incredibly high, reaching nearly 50%.
Currently available mechanical circulatory support devices can replace the function of the heart and/or lungs, thereby essentially eliminating the primary cause. However, cardiogenic shock is not only an isolated decrease in cardiac function but a rapidly progressing multiorgan dysfunction accompanied by severe cellular and metabolic abnormalities. The window for successful treatment is relatively narrow and when missed, even the elimination of underlying primary cause is not enough to reverse this vicious circle.
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News
Our paper was published in EHJ: Digital Health
Our abstract was presented in the Late Breaking Science section at the ESC 2024 congress in London
For the very first time, groundbreaking original research from Slovakia has been showcased in the prestigious ESC Late Breaking Science session.
Additionally, the study has garnered attention from Slovak mainstream media, highlighting its relevance and impact beyond the scientific community.
Projekt slovenských vedcov sa dostal medzi najvýznamnejšie kardiologické štúdie sveta | OZDRAVME.SK
#STOPSHOCK was chosen for the SHOCK TANK at the THT 2025
What we acomplished so far
After external validation, our model showed an exciting predictive capability: AUC of 0.84 surpassing current validated CS models (e.g., the ORBI score).
We started an international cooperation not only in the framework of patient data collection but also in the planning, design, and management of the entire #STOPSHOCK project.
Our online cloud-based electronic case report form is up and running, continually tested, and ready for final variable selection.
The online calculator is online.
Smartphone apps were officially released (for Android and iOS)
New potential CS predictors can be added and tested to ensure that the model keeps pace with contemporary research. We are currently working on external validation of the updated STOPSHOCK 2.0 with very promising preliminary results
eCRF is up and running with more than 6.5k patients enrolled
Our Papers:
"Data processing pipeline for cardiogenic shock prediction using machine learning"
"Machine-learning based scoring system to predict cardiogenic shock in acute coronary syndrome"
Where have we presented our results?
2022 ESC Acute CardioVascular Care
ESC ACVC 2023, Marseille, France
AHA 2023, Philadelphia, PA
ESC ACVC 2024
ESC 2024, London, UK
Our Awards:
The American Heart Association 2023 Paul Dudley White International Scholar Award for our abstract!
Where are we heading?
THT 2025 - Technology and Heart Failure Therapeutics
Support us
Sign-up your institution for prospective validation
Get access to dedicated STOP SHOCK smartphone applications and work with us on prospective validation and continuous model improvement.
Sign-up your institution for STOP SHOCK CS registry
Help with retrospective or prospective patient registration. Established ACS STOP SHOCK patient database will be available to all contributing members with STOP SHOCK not being the end but a beginning of international research cooperation on cardiogenic shock.
Download the app
Privacy Policy
Online calculator
For test use only. Manuscript with scientific evidence is currently in the publication process
#STOPSHOCK
Score To Predict SHOCK