Cardiogenic shock is a serious, life-threatening condition affecting almost 10% of patients suffering from acute coronary syndrome. When untreated, it can rapidly progress causing collapse of circulation and sudden death.
Despite contemporary improvements in diagnostic and treatment options, mortality remains incredibly high, reaching nearly 50%. The window for successful treatment is relatively narrow — when missed, even eliminating the underlying primary cause is not enough to reverse this vicious circle.
Currently available mechanical circulatory support devices can replace the function of the heart and/or lungs, thereby essentially eliminating the primary cause. However, cardiogenic shock involves not only an isolated decrease in cardiac function but a rapidly progressing multiorgan dysfunction accompanied by severe cellular and metabolic abnormalities.
#STOPSHOCK is a novel, continuously updated AI-based scoring system for the prediction of cardiogenic shock in patients with acute coronary syndrome.

The ability to identify high-risk patients prior to the development of CS allows pre-emptive measures — such as implantation of pMCS — and thus prevents shock, leading to improved survival.
⬇ CLICK ON THE GRAPHICAL ABSTRACT
PUBLISHED
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TO BE PUBLISHED
| STOPSHOCK 2.0 external validation — very promising preliminary results |
#STOPSHOCK presented at Late Breaking Science section at THT 2026

Great atmosphere and inspiring discussions at AdvanceMed 2026 (Ostrava, April 9 - 10). We were also proud to present STOPSHOCK (MUDr. Andrej Domonkos), which received very positive feedback and strong interest from clinicians.

#STOPSHOCK was chosen for the SHOCK TANK at the THT 2025
Our abstract was presented in the Late Breaking Science section at the ESC 2024 congress in London.
For the very first time, groundbreaking original research from Slovakia has been showcased in the prestigious ESC Late Breaking Science session. Additionally, the study has garnered attention from Slovak mainstream media, highlighting its relevance and impact beyond the scientific community:
Projekt slovenských vedcov sa dostal medzi najvýznamnejšie kardiologické štúdie sveta | OZDRAVME.SK
Online cloud-based eCRF up and running — 6,500+ patients enrolled
External validation — AUC of 0.84, surpassing the ORBI score
International cooperation established
Online risk calculator live and available ⬇ at the bootom of this page
Smartphone apps officially released (iOS & Android) ⬇ at the bootom of this page
Paper published in EHJ: Digital Health
STOPSHOCK 2.0 external validation — very promising preliminary results
Pre-emptive implantation of Impella CP (RCT) — planned
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AHA Paul Dudley White International Scholar Award
2023 · American Heart Association
Awarded for our abstract at the AHA 2023 Scientific Sessions in Philadelphia..

We invite clinicians and institutions worldwide to collaborate with us on prospective validation and continuous model improvement.
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#STOPSHOCK
Score To Predict SHOCK